Background We conducted a systematic review and meta-analysis to clarify the risk of early
and late cardiotoxicity of anthracycline agents in patients treated for breast or ovarian …

Background—Evidence regarding the use of direct oral anticoagulants (DOACs) in the
elderly, particularly bleeding risks, is unclear despite the presence of greater comorbidities …

Background: The achievement of adequate nutritional intakes in preterm infants is
challenging and may explain the poor growth often seen in this group. The use of early …

Background Few data exist on the comparative safety and immunogenicity of different
COVID-19 vaccines given as a third (booster) dose. To generate data to optimise selection …

Objective To examine the prevalence of, and risk factors for, depression and anxiety in
women with early breast cancer in the five years after diagnosis. Design Observational …

Background Some high-income countries have deployed fourth doses of COVID-19
vaccines, but the clinical need, effectiveness, timing, and dose of a fourth dose remain …

Background: Bipolar disorder (BD) is a leading cause of disability. Systematic reviews of
randomized trials for the treatment of the maintenance phase of BD are lacking. Objectives …

Objective To obtain evidence whether the online pulmonary rehabilitation (PR) programme
'my-PR'is non-inferior to a conventional face-to-face PR in improving physical performance …

Psychoeducational interventions for family carers of people with psychosis are effective for
improving compliance and preventing relapse. Whether carers benefit from these …

The widespread distribution and relapsing nature of Plasmodium vivax infection present
major challenges for the elimination of malaria. To characterize the genetic diversity of this …