Objectives: This study evaluated the associations of obesity and cardiometabolic traits with
incident heart failure with preserved versus reduced ejection fraction (HFpEF vs. HFrEF) …

Background: Patients with isolated tricuspid regurgitation (TR) in the absence of left-sided
valvular dysfunction are often managed nonoperatively. Objectives: The purpose of this …

Importance Nearly half of all patients with heart failure have preserved ejection fraction
(HFpEF) as opposed to reduced ejection fraction (HFrEF), yet associations of biomarkers …

Aims While heart failure with preserved (HFpEF) and reduced ejection fraction (HFrEF) are
well described, determinants and outcomes of heart failure with mid‐range ejection fraction …

Type 2 diabetes is characterized by insulin resistance and a gradual loss of pancreatic beta
cell mass and function,. Currently, there are no therapies proven to prevent beta cell loss …

Background: Differences in proteomic profiles between men and women may provide
insights into the biological pathways that contribute to known sex differences in …

Objective Hydrothermal duodenal mucosal resurfacing (DMR) is a safe, outpatient
endoscopic procedure. REVITA-2, a double-blind, superiority randomised controlled trial …

Abstract Background: Galectin-3 (Gal-3) has been associated with heart failure (HF) and
poor cardiovascular outcomes. However, the effect of longitudinal changes in Gal-3 on …

Background Experimental studies support a link between obesity and pulmonary
hypertension (PH), yet clinical studies have been limited. This study sought to determine the …

Aims Duodenal mucosal resurfacing (DMR) is an endoscopic procedure developed to
improve metabolic parameters and restore insulin sensitivity in patients with diabetes. Here …