User profiles for "author:Vikas Kapil"

Vikas Kapil

Clinical Senior Lecturer in Clinical Pharmacology & Cardiovascular Medicine
Verified email at qmul.ac.uk
Cited by 6444

Immune boosting by B. 1.1. 529 (Omicron) depends on previous SARS-CoV-2 exposure

CJ Reynolds, C Pade, JM Gibbons, AD Otter, KM Lin… - Science, 2022 - science.org
The Omicron, or Pango lineage B. 1.1. 529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …

Current Perspectives on Coronavirus Disease 2019 and Cardiovascular Disease: A White Paper by the JAHA Editors

AK Gupta, H Jneid, D Addison, H Ardehali… - Journal of the …, 2020 - Am Heart Assoc
Abstract Coronavirus Disease 2019 (COVID‐19) has infected more than 3.0 million people
worldwide and killed more than 200,000 as of April 27, 2020. In this White Paper, we …

Impacts of climate change on public health in India: future research directions

KF Bush, G Luber, SR Kotha, RS Dhaliwal… - Environmental …, 2011 - ehp.niehs.nih.gov
Background Climate change and associated increases in climate variability will likely further
exacerbate global health disparities. More research is needed, particularly in developing …

Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO

V Kapil, AB Milsom, M Okorie, S Maleki-Toyserkani… - …, 2010 - Am Heart Assoc
Ingestion of dietary (inorganic) nitrate elevates circulating and tissue levels of nitrite via
bioconversion in the entero-salivary circulation. In addition, nitrite is a potent vasodilator in …

Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study

V Kapil, RS Khambata, A Robertson, MJ Caulfield… - …, 2015 - Am Heart Assoc
Single dose administration of dietary inorganic nitrate acutely reduces blood pressure (BP)
in normotensive healthy volunteers, via bioconversion to the vasodilator nitric oxide. We …

[HTML][HTML] Physiological role for nitrate-reducing oral bacteria in blood pressure control

V Kapil, SMA Haydar, V Pearl, JO Lundberg… - Free Radical Biology …, 2013 - Elsevier
Circulating nitrate (NO3−), derived from dietary sources or endogenous nitric oxide
production, is extracted from blood by the salivary glands, accumulates in saliva, and is then …

Non-pharmacological factors for hypertension management: a systematic review of international guidelines

C Maniero, A Lopuszko, KB Papalois… - European journal of …, 2023 - academic.oup.com
Lifestyle modifications are one of the cornerstones of hypertension prevention and
treatment. We aimed to systematically review hypertension guidelines on their …

Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential

SM Ghosh, V Kapil, I Fuentes-Calvo, KJ Bubb… - …, 2013 - Am Heart Assoc
Elevation of circulating nitrite (NO2−) levels causes vasodilatation and lowers blood
pressure in healthy volunteers. Whether these effects and the underpinning mechanisms …

[HTML][HTML] Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans

KS Rathod, V Kapil, S Velmurugan… - The Journal of …, 2023 - Am Soc Clin Investig
BACKGROUND. Cardiovascular disease occurs at lower incidence in premenopausal
females compared with age-matched males. This variation may be linked to sex differences …

[HTML][HTML] Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy …

RK Gupta, J Rosenheim, LC Bell, A Chandran… - The Lancet …, 2021 - thelancet.com
Background We hypothesised that host-response biomarkers of viral infections might
contribute to early identification of individuals infected with SARS-CoV-2, which is critical to …