Galectins are a family of soluble β‐galactoside‐binding lectins that play many important
regulatory roles in inflammation, immunity, and cancer. Recently, a role for galectin‐3 in the …

Advances in cardiovascular research have identified oxidative stress as an important
pathophysiological pathway in the development and progression of heart failure. Oxidative …

Aging is a biological process that affects most cells, organisms and species. Telomeres have
been postulated as a universal biological clock that shortens in parallel with aging in cells …

Blood pressure is a heritable trait influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …

Background—For the general population, the clinical relevance of an increased urinary
albumin excretion rate is still debated. Therefore, we examined the relationship between …

Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …

Background The effects of pharmacological blood pressure lowering at normal or high-
normal blood pressure ranges in people with or without pre-existing cardiovascular disease …

Abstract Background The European Society of Cardiology (ESC) has published guidelines
for the investigation of patients with suspected heart failure and, if the diagnosis is proven …

Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer
and several age-associated diseases. We report here a genome-wide meta-analysis of …

Hillege HL, Janssen WMT, Bak AAA, Diercks GFH, Grobbee DE, Crijns HJGM, van Gilst WH,
de Zeeuw D, de Jong PE for the PREVEND Study group (University of Groningen and …