Introduction: While catheter tip/tissue contact has been shown to be an important
determinant of ablative lesions in in vitro studies, the impact of contact on the outcomes of …

The Japanese Circulation Society (JCS) published the “Guidelines for Pharmacological
Treatment of Arrhythmia” in 2004, and a revised edition was published in 2009. 1 Both …

MMP‐2 Predicts the Outcome of AF Ablation. Introduction: Although catheter ablation can
effectively eliminate atrial fibrillation (AF), the progression of atrial remodeling increases the …

Background: Whether epicardial adipose tissue (EAT) is independently associated with
atrial fibrillation (AF) and outcome after catheter ablation (CA) for AF remains unclear …

Background—Although increased epicardial adipose tissue (EAT) volume is known to be
associated with increased prevalence of atrial fibrillation (AF), the exact mechanisms are …

Background Large-scale investigations on the use of oral anticoagulants including direct
oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) have not included …

Background: Although direct oral anticoagulants (DOACs) are widely used in Japanese
patients with atrial fibrillation (AF), large-scale investigations into their use, with suitable …

Aims Pulmonary hypertension (PH) and pulmonary vascular remodelling are common in
patients with heart failure with preserved ejection fraction (HFpEF). Many patients with …

Background: Off-label dosing of direct oral anticoagulants (DOACs) is encountered clinically
among patients with atrial fibrillation (AF), although data on the clinical outcomes of over …

Cardiac resynchronization therapy (CRT) has been established as a standard treatment for
heart failure. The effectiveness of CRT has been shown in many clinical trials and realized in …