User profiles for "author:Yong Chul Kim"

Yong-Chul Kim

Professor, Gwangju Institute of Science & Technology
Verified email at gist.ac.kr
Cited by 8203

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

KA Jacobson, KS Park, JL Jiang, YC Kim, ME Olah… - …, 1997 - Elsevier
The effects of putative A3 adenosine receptor antagonists of three diverse chemical classes
(the flavonoid MRS 1067, the 6-phenyl-1, 4-dihydropyridines MRS 1097 and MRS 1191 …

P2X7 receptor antagonists: a patent review (2010–2015)

JH Park, YC Kim - Expert opinion on therapeutic patents, 2017 - Taylor & Francis
ABSTRACT Introduction: The P2X7 receptor (P2X7R) is a unique subtype among the family
of seven purinergic P2X receptors, which are ATP-gated non-selective cation channels …

Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection

H Masutani, J Bai, YC Kim, J Yodoi - Molecular neurobiology, 2004 - Springer
Oxidative stress has been implicated in the pathogenesis of a wide variety of neuronal
diseases, including ischemic neuronal injury, Alzheimer's disease, and Parkinson's disease …

[HTML][HTML] Hemin-induced activation of the thioredoxin gene by Nrf2: a differential regulation of the antioxidant responsive element by a switch of its binding factors

YC Kim, H Masutani, Y Yamaguchi, K Itoh… - Journal of Biological …, 2001 - ASBMB
Thioredoxin plays an important role in various cellular processes through redox regulation.
Here, we have demonstrated that thioredoxin expression is transcriptionally induced in K562 …

Experimental investigation of aerodynamic forces and wind pressures acting on tall buildings with various unconventional configurations

H Tanaka, Y Tamura, K Ohtake, M Nakai… - Journal of Wind …, 2012 - Elsevier
Tall buildings have been traditionally designed to be symmetric rectangular, triangular or
circular in plan, in order to avoid excessive seismic-induced torsional vibrations due to …

Micromachined piezoelectric membrane acoustic device

SC Ko, YC Kim, SS Lee, SH Choi, SR Kim - Sensors and Actuators A …, 2003 - Elsevier
This paper reports on a 3 mm× 3 mm× 0.003 mm piezoelectric membrane acoustic device,
which works as a microphone and a microspeaker. It has a 0.5 μm thick zinc oxide (ZnO) …

Thermosoftening treatment of the nasotracheal tube before intubation can reduce epistaxis and nasal damage

YC Kim, SH Lee, GJ Noh, SY Cho, JH Yeom… - Anesthesia & …, 2000 - journals.lww.com
We evaluated whether a thermosoftening treatment with warm saline of a nasotracheal
preformed tube can improve navigability through the nasal passageways and reduce …

[HTML][HTML] Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice

M Tanito, H Masutani, YC Kim… - … & visual science, 2005 - iovs.arvojournals.org
purpose. Thioredoxin (Trx) is a multifunctional endogenous redox regulator that protects
cells against various types of cellular or tissue stresses. This study was conducted to test …

Anilide Derivatives of an 8-Phenylxanthine Carboxylic Congener Are Highly Potent and Selective Antagonists at Human A2B Adenosine Receptors

YC Kim, X Ji, N Melman, J Linden… - Journal of medicinal …, 2000 - ACS Publications
No highly selective antagonists of the A2B adenosine receptor (AR) have been reported;
however such antagonists have therapeutic potential as antiasthmatic agents. Here we …

Structure–activity relationships of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists

KY Jung, SK Kim, ZG Gao, AS Gross, N Melman… - Bioorganic & medicinal …, 2004 - Elsevier
4-(4-Methoxyphenyl)-2-aminothiazole and 3-(4-methoxyphenyl)-5-aminothiadiazole
derivatives have been synthesized and evaluated as selective antagonists for human …