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Takayasu’s arteritis: management of left main stem stenosis
  1. I S Malik1,
  2. O Harare2,
  3. A AL-Nahhas3,
  4. K Beatt4,
  5. J Mason2
  1. 1Waller Department of Cardiology, St Mary’s Hospital, London, UK
  2. 2Department of Rheumatology, Hammersmith Hospital, London, UK
  3. 3Department of Nuclear Medicine, Hammersmith Hospital
  4. 4Department of Cardiology, Hammersmith Hospital
  1. Correspondence to:
    Dr I Malik, Waller Department of Cardiology, Mary Stanford Wing, St Mary’s Hospital, Praed Street, London W2 1NY, UK;
    i.malik{at}ic.ac.uk

Abstract

Takayasu arteritis is a chronic vasculitis involving the aorta and its main branches, the pulmonary arteries, and the coronary tree, and needs to be considered in a young patient with angina, in particular when pulses are absent. This case illustrates the limitations of exercise testing in diagnosing the extent of coronary artery disease and the risks associated with coronary angiography in patients with inflammatory disease in the left main stem coronary artery. It also highlights the novel use of non-invasive scanning with positron emission tomography using 18-fluorodeoxyglucose in assessing remission from this disease. Revascularisation was performed with percutaneous transluminal coronary angioplasty and stenting as an emergency procedure, but treatment of the restenosis with directional atherectomy was based on a review of the available literature. The lymphocytic alveolitis seen in this patient has not been previously described in Takayasu’s disease.

  • Takayasu’s arteritis
  • left main stem stenosis
  • FDG-PET, positron emission tomography using 18-fluorodeoxyglucose
  • LMS, left main stem
  • PTCA, percutaneous transluminal coronary angioplasty

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