Best Research Paper Award

Each year the Heart editorial team selects the most meritorious research papers to receive the Heart Best Research Paper Award. Primary considerations are the relevance of the clinical question addressed by the research, the quality of the research study design and data presentation, and the interest generated by the paper among other researchers, clinical cardiologists and the general public.

We are pleased to announce the winner and finalists for the Heart Best Research Paper Award 2021 in recognition of high quality and clinical impact. The 2021 award is for the best research paper published in the journal in 2020.

You can read more about these papers and their authors in this article from the Heart Editor-in-Chief, Catherine Otto.


Julia Hippisley-Cox, Duncan Young, Carol Coupland, Keith M Channon, Pui San Tan, David A Harrison, Kathryn Rowan, Paul Aveyard, Ian D Pavord, Peter J Watkinson
Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people
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Åsa K Hedman, Camilla Hage, Anil Sharma, Mary Julia Brosnan, Leonard Buckbinder, Li-Ming Gan, Sanjiv J Shah, Cecilia M Linde, Erwan Donal, Jean-Claude Daubert, Anders Mälarstig, Daniel Ziemek, Lars Lund
Identification of novel pheno-groups in heart failure with preserved ejection fraction using machine learning
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Gal Tsaban, Anat YaskolkaMeir, Ehud Rinott, Hila Zelicha, Alon Kaplan, Aryeh Shalev, Amos Katz, Assaf Rudich, Amir Tirosh, Ilan Shelef, Ilan Youngster, Sharon Lebovitz, Noa Israeli, May Shabat, Dov Brikner, Efrat Pupkin, Michael Stumvoll, Joachim Thiery, Uta Ceglarek, John T Heiker, Antje Körner, Kathrin Landgraf, Martin von Bergen, Matthias Blüher, Meir J Stampfer, Iris Shai
The effect of green Mediterranean diet on cardiometabolic risk; a randomised controlled trial
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2020 winner

Ralph Kwame Akyea, Joe Kai, Nadeem Qureshi, Barbara Iyen, Stephen F Weng
Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease
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2019 winner

Sean Lee Zheng, Fiona T. Chan, Adam A. Nabeebaccus, Ajay M. Shah, Theresa McDonagh, Darlington O. Okonko, Salma Ayis
Drug treatment effects on outcomes in heart failure with preserved ejection fraction: a systematic review and meta-analysis
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2018 winner

Elizabeth Mostofsky, Martin Berg Johansen, Anne Tjønneland, Harpreet S. Chahal, Murray A. Mittleman, Kim Overvad
Chocolate intake and risk of clinically apparent atrial fibrillation: the Danish Diet, Cancer, and Health Study
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2017 winner

Nicole K Valtorta, Mona Kanaan, Simon Gilbody, Sara Ronzi, Barbara Hanratty
Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies
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2016 joint winners

Edward W Carlton, Louise Cullen, Martin Than, James Gamble, Ahmed Khattab, Kim Greaves
A novel diagnostic protocol to identify patients suitable for discharge after a single high-sensitivity troponin
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Chun Shing Kwok, S Matthijs Boekholdt, Marleen A H Lentjes, Yoon K Loke, Robert N Luben, Jessica K Yeo, Nicholas J Wareham, Phyo K Myint, Kay-Tee Khaw
Habitual chocolate consumption and risk of cardiovascular disease among healthy men and women
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2015 winner

Sonia Bouri, Matthew James Shun-Shin, Graham D. Cole, Jamil Mayet and Darrel P. Francis
Meta-analysis of secure randomised controlled trials of ß-blockade to prevent perioperative death in non-cardiac surgery
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